osmotic demyelination syndrome following correction of hyponatremia
N Engl J Med 2015; 372:55. Lithium official prescribing information for healthcare professionals. from C L Hyponatremia is an important electrolyte abnormality with the potential for significant morbidity and mortality. Disorders of plasma sodium--causes, consequences, and correction. Hypernatremia Definition Hypernatremia is an imbalance in electrolyte, where the sodium level gets elevated in the blood. Rapid correction of hyponatremia is a known risk factor for the development of osmotic demyelination syndrome (ODS),[1] a disorder characterized by the wide spread development of demyelination in the pontine as well as the extra-pontine regions. Medicine (Baltimore) 1993; 72:359. Richard H. Sterns, M.D., Jack E. Riggs, There are no proven effective Hyponatremia is most commonly associated with states of hypotonicity; however, it can also occur in states of normal or high osmolarity. Osmotic demyelination syndrome following correction of hyponatremia. Original Article. Richard H. Sterns, M.D., Jack E. Riggs, M.D., and Sydney S. Hypokalemia may predispose patients to develop osmotic demyelination following correction of hyponatremia. Includes: indications, dosage, adverse reactions, pharmacology and more. Review of Drug-Induced Hyponatremia (Am J Kid Dis 2008;52:144) treatment of chronic hyponatremia . However, even slow correction of hyponatremia can result in ODS. He subsequently developed osmotic demyelination syndrome. Disorders of Plasma Sodium Causes, Consequences, and Correction [Central pontine myelinolysis and hyponatremia]. Generally, hypernatremia do not occur Hyponatremia is among the most common electrolyte abnormalities in children. OBJECTIVE. Therapeutic recommendations for management of severe hyponatremia: current concepts on pathogenesis and prevention of neurologic complications. Drops in another review. Osmotic demyelination syndrome following slow correction of hyponatremia: Possible role of hypokalemia. Severe hyponatraemia carries a risk of cerebral oedema with a significant mortality, yet correcting it too rapidly can result in osmotic demyelination syndrome In neurologically stable patients with severe hyponatremia, it may be beneficial to correct hypokalemia prior to correction of the serum sodium. Hyponatremia. Julie R. Ingelfinger, M.D., Editor. Sterns RH, Riggs JE, Schochet SS Jr. Osmotic Demyelination Syndrome Following Correction of Hyponatremia. The differential diagnosis of patients presenting with acute encephalopathy is broad. Original Article. Osmotic Demyelination Syndrome Following Correction of Hyponatremia: Association With Hypokalemia James W. Lohr, MD, Buffalo, New York The osmotic demyelination syndrome (ODS) is a neurologic complication associated with rapid correction of hyponatremia. Following supportive treatment he made a full recovery. The osmotic demyelination syndrome (ODS) has been a recognized complication of the rapid correction of hyponatremia for decades. Hyponatremia is defined as a serum or plasma sodium less than 135 mEq/L. The etiology of this complication is unclear. Karp BI, Laureno R. Pontine and extrapontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia. Osmotic Demyelination Syndrome Following Correction of Hyponatremia: Association With Hypokalemia James W. Lohr, MD, Buffalo, New York Radiological Reasoning: Hyperintensity of the Basal Ganglia and Cortex on FLAIR and Diffusion-Weighted Imaging Osmotic demyelination syndrome ... may follow too-rapid correction of hyponatremia. The treatment of hyponatremia is controversial: some authorities have cautioned that rapid correction causes central pontine myelinolysis, and others warn that severe hyponatremia has a high mortality Learn about Samsca (Tolvaptan Tablets ) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Best review. N Engl J Med 1986; 314:1535. The effects of late radiation injury to the brain are first detected on imaging studies about 6 to 8 months following the initial therapy. Osmotic demyelination syndrome (ODS) primarily occurs after rapid correction of severe hyponatremia. ETIOLOGY. Sterns RH. Sterns RH, Riggs JE, Schochet SS Jr. Osmotic demyelination syndrome following correction of hyponatremia. Disorders of Fluids and Electrolytes. Osmotic Demyelination Syndrome Following Correction of Hyponatremia. Learn about Samsca (Tolvaptan Tablets ) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Osmotic demyelination syndrome following ... Hemiparesis apparently due to central pontine myelinolysis following ... syndrome following correction of hyponatremia. The term osmotic demyelination syndrome is used ... by osmotic effects in the setting of correction of ... syndrome following correction of hyponatremia. Review Article. Imaging can help in narrowing the differential in many cases. Osmotic demyelination syndrome following correction of hyponatremia: association with hypokalemia. Hyponatremia is decrease in serum sodium concentration 136 mEq/L caused by an excess of water relative to solute.